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or male breast cancer. This gene can be passed on by either the male or female parent. Patients with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome have a 3.5 fold increase in the risk of ovary tumors. (Of note, their lifetime risk of uterine cancer can be as high as 60%). Removal of both ovaries and fallopian tubes is the most effective method to prevent the malignant ovarian disease in hereditary cases.

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